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Research & Science: The Impact of Ketamine Infusion Therapy

Explore in-depth resources, news articles, and scientific studies on ketamine infusion therapy as a groundbreaking treatment for conditions such as depression, PTSD, anxiety, fibromyalgia, and suicidal ideation.

How Ketamine Therapy Works for Long-Term Relief

Ketamine provides lasting relief from mood and pain symptoms by blocking pain signal transmission and elevating key neurochemicals that enhance mood.

Safe and Monitored Treatment

Administered in subanesthetic doses, ketamine therapy is monitored by a qualified anesthesia professional. Patients report minimal side effects, making it a safe alternative to traditional treatments.

Fast-Acting and Effective for Mental Health and Pain

Ketamine infusion therapy can produce noticeable improvements within hours, offering critical relief for individuals suffering from pain and mental health challenges.

Conditions Treated with Ketamine Therapy:

  • Depression: A common mental health condition often resistant to traditional treatments. Ketamine offers a rapid, effective alternative for lasting symptom relief.
  • Chronic Pain Syndromes (e.g., CRPS, Fibromyalgia): Reduces persistent pain unresponsive to other therapies.
  • Headaches & Migraines: Alleviates pain and improves quality of life.
  • Obsessive-Compulsive Disorder (OCD): Supports symptom reduction in treatment-resistant cases.
  • Post-Traumatic Stress Disorder (PTSD): Provides relief from trauma-related symptoms.
  • Substance Abuse & Addiction: Helps with cravings and underlying mental health conditions.
  • Suicidal Ideation: Offers immediate help for individuals experiencing severe mental health crises.

Depression Facts & Research Insights:

  • Approximately 16 million adults experienced a major depressive episode in 2014 (NIMH).
  • Only 30-40% of patients respond to traditional antidepressants after a full course.
  • Depression is the leading cause of disability worldwide (WHO).
  • Suicide ranks as the 10th leading cause of death across all ages in the U.S. (CDC).

For further reading and research, browse our collection of Research Articles detailing the science behind ketamine infusion therapy and its impact on mental health and chronic pain conditions.

Research Articles on Ketamine Efficacy

Safety and tolerability of IV ketamine in adults with major depressive or bipolar disorder: results from the Canadian rapid treatment center of excellence


The effectiveness of repeated intravenous ketamine on depressive symptoms, suicidal ideation and functional disability in adults with major depressive disorder and bipolar disorder: Results from the Canadian Rapid Treatment Center of Excellence


Ketamine has potential therapeutic role in adolescents with treatment-resistant depression


Ketamine for Pain Management, Treatment of Depression


Medical Daily: Ketamine Helps Patients With Bipolar Disorder, Depression, But Works Differently Among The Two by S. Castillo


National Institute of Mental Health: Ketamine Lifts Depression via a Byproduct of its Metabolism


WebMD: Ketamine: The Future of Depression Treatment? by Matt McMillen


National Institute of Mental Health: Rapid Agent Restores Pleasure-seeking Ahead of Other Antidepressant Action


VICE: I Used Ketamine to Treat My Depression by Brent Miles & Troy Farah


The Journal of the American Society of Anesthesiologists, Inc.: Ketamine Metabolomics in the Treatment of Major Depression by Monique van Velzen, PhD & Albert Dahan, MD, PhD

Suicidal Ideation

Medical News Today: Ketamine ‘rapid and effective’ for reducing suicidal thoughts by Honor Whiteman


J Clin Psychiatry: Rapid Resolution of Suicidal Ideation after a Single Infusion of an NMDA Antagonist in Patients with Treatment-Resistant Major Depressive Disorder by Nancy DiazGranados, MD et. al.


Digital Access to Scholarship at Harvard: Effects of Intravenous Ketamine on Explicit and Implicit Measures of Suicidality in Treatment-Resistant Depression by Rebecca B. Price, Matthew K. Nock, et al


The International Journal of Neuropsychopharmacology: A preliminary naturalistic study of low-dose ketamine for depression and suicide ideation in the emergency department by Gregory Luke Larkin & Annette L. Beautrais

Postpartum Depression

Medscape: Postpartum Depression by Saju Joy, MD

Bipolar Depression

Medical Daily: Ketamine Helps Patients With Bipolar Disorder, Depression, But Works Differently Among The Two by Stephanie Castillo

Treatment-resistant Depression

The American Journal of Psychiatry: A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression by Jaskaran B. Singh, MD, Maggie Fedgchin, PharmD, et al